Bacillus thurengiensis: Biotechnologocal applications and potentials
Bacillus thurengiensis: Biotechnologocal applications and potentials
Volume 3, Issue 2, 2021, Page 36 - 52
Authors : Masoumeh Dehghani , Reyhaneh Ghorbani zavareh , Maryam Sadat Jalili Tabaii , Maryam Sadat mirbagheri Firozabad

Abstract :
Bacillus thuringiensis is a gram-positive bacterium of spores, which produces crystalline parasporic proteins during the sporulation process and is known as an important microbial insecticide, which plays an important role in combating agricultural pests. Biological control of insecticide-resistant Anopheles mosquitoes with the help of Bt in medicine is very effective in controlling malaria. Bt is biologically active against parasites and the deltatoxin of this bacterium can be used to treat leishmaniasis infections or to treat ascariasis caused by ascariasis parasitic worms due to its cytosidal effects against leishmania parasite promastigotes. In addition to Cry crystalline proteins, Bt is able to produce paraspores, which, unlike the first group, have no insecticidal properties and have anti-cancer effects in humans. The protein / glycoprotein surface layer in this bacterium can be widely used in nanobiotechnology. It is also important in the bioremediation of contaminated environments due to the biological absorption of heavy metals (copper, manganese, cadmium, nickel) which are soluble in industrial effluents and have a high durability in nature and a high tendency to accumulate in the tissues of living organisms. Biodegradation of biological wastes such as ethidium bromide and methylene blue, pharmaceutical effluents such as ibuprofen, synthetic pesticide residues such as halothane, malathion, as well as biodegradation of light petroleum polymers from the sea surface and biodegradable biomass biomass biomass Other applications of this bacterium and also having different enzymes such as: lipase, alpha-amylase, creatinase, protease and cellulase can be used in food, cosmetics, detergents, paper production, biogas production and medicine. Simultaneous production of several widely used types of polyhydroxyalkanoate by Bt strains as environmentally friendly microbial biopolymers to replace petroleum-derived plastics is another application of this microorganism. Bt can help us fight antibiotic resistance by producing bacteriocin and antimicrobial peptides. Bt plays an important role in creating microbial pathways for the production of silver nanoparticles for antimicrobial applications and nanobiological insecticides.

Keywords :
Bacillus thurengiensis applications, Crystalin proteins, Biotechnology